Steroid responsiveness of peripheral blood T cells derived from steroid sensitive, steroid dependent, and steroid resistant asthmatics, and induction of steroid resistance by costimulatory signal
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Steroid responsiveness of peripheral blood T cells derived from steroid sensitive, steroid dependent, and steroid resistant asthmatics, and induction of steroid resistance by costimulatory signal
Steroid responsiveness of peripheral blood T cells derived from steroid sensitive, steroid dependent, and steroid resistant asthmatics, and induction of steroid resistance by costimulatory signal Akio Mori, Akemi Abe, Satoshi Kouyama, Miyako Yamaguchi, Yo Iijima, Chihiro Mitsui, Chiyako Oshikata, Hidenori Tanimoto, Kiyoshi Sekiya, Takahiro Tsuburai, Masami Taniguchi, Mamoru Ohtomo, Yuji Maeda, ...
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The current study examined whether alterations in glucocorticoid receptor (GR) binding contribute to poor response to glucocorticoid therapy in asthma. 29 asthma patients with forced expiratory volume in 1 s (FEV1) < 70% predicted were studied. Patients were classified as steroid sensitive (SS) if their morning FEVI increased > 30% after a I-wk course of oral prednisone 20 mg twice daily and st...
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ژورنال
عنوان ژورنال: Clinical and Translational Allergy
سال: 2013
ISSN: 2045-7022,2045-7022
DOI: 10.1186/2045-7022-3-s1-p5